Alchemy

From Uopedia

As with all crafting skill raising – craft the item that uses the least resources and gives you at least 0.1% chance to fail.

Have a bottle and a keg handy and that way you can empty the full bottle into the keg and sell it if you wish. Alternatively when you get to the Greater potions, they will be handy for plant growing and beekeeping.

This is one suggested route – taken from the manual at the Player's Library.

• Buy the skill from an Alchemist (Britain or Moonglow have alchemists) – this should take you to about 30.

• Make Lesser Cure using 1 garlic to 40.0 skill by which time you will be at 100% success for that.

• Make Lesser Poison using 1 nightshade to 45.0 skill (100% success).

• Make Lesser Agility using 1 bloodmoss to 65.0 skill (100% success).

• Make Lesser Strength using 2 mandrake to 75.0 skill (100% success).

• Make Greater Agility using 3 bloodmoss to 85.0 skill (100% success).

• Make Greater Poison using 3 nightshade to 100.0 skill (100% success). Alternatively you could make Greater Strength potions to 95.0 which use up more reagents but have a higher success rate. At this point you need to revert to Greater Poison to GM the skill.

• Make Greater Poison using 3 nightshade to 105.0 skill (100% success).

• Make Greater Cure using 6 garlic to 115.0 skill (100% success).

• Make Deadly Poison using 8 nightshade to 120.0 skill (100% success).

Further details regarding macros and amount of resources used can be found in the Player's Library book.